SCHEMBL21189243

SCHEMBL21189243

CC1(C)CC(C)(C)NC(C)(C)CC(C)(C)N1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243842 0.95
SCHEMBL3834092 0.84 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL11372652 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL11462732 0.78 ALDH1A1 (0.36) ALDH1A1
SCHEMBL7560236 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL1232618 0.78 ALDH1A1 (0.36) ALDH1A1
Ethane SCHEMBL18784636 0.75 ALDH1A1 (0.35) ALDH1A1
SCHEMBL11361955 0.73
SCHEMBL22400289 0.73
SCHEMBL12910995 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021105497-A1 SMALL-MOLECULE NADPH OXIDASE 2 INHIBITORS UNIVERSITY OF COPENHAGEN (DK) 2021-06-03 WO disclosed
US-20200348294-A1 HYPERCROSSLINKING WITH DIAMINE CROSSLINKERS ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2020-11-05 US disclosed
WO-2019141779-A1 HYPERCROSSLINKING WITH DIAMINE CROSSLINKERS F. HOFFMANN-LA ROCHE AG (CH) 2019-07-25 WO disclosed