Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243842 | 0.88 | — | — | |
| SCHEMBL21189243 | 0.84 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11372652 | 0.74 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1232618 | 0.72 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL7560236 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11462732 | 0.72 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL12676626 | 0.71 | — | — | |
| Ethane SCHEMBL18784636 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11771323 | 0.69 | — | — | |
| SCHEMBL1133789 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222927-B1 | Pharmaceutical compositions having appetite suppressant activity | CSIR (ZA) | 2013-11-20 | — | — | EP | disclosed |
| EP-1213020-B1 | Compounds and pharmaceutical compositions having appetite suppressant activity | CSIR (ZA) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007088130-A1 | USE OF SECONDARY STERICALLY HINDERED AMINES AS PROCESSING ADDITIVES IN ROTOMOLDING PROCESSES | CIBA HOLDING INC. (CH) | 2007-08-09 | — | — | WO | disclosed |
| US-7166611-B2 | Plant extract comprising steroidal glycosides from the genus Trichocaulon or Hoodia produced by solvent extraction | CSIR (ZA) | 2007-01-23 | — | — | US | disclosed |
| US-20060205931-A1 | Pharmaceutical compositions having appetite suppressant activity | CSIR | 2006-09-14 | — | — | US | disclosed |
| EP-1598054-A2 | Method of suppressing appetite | CSIR (ZA) | 2005-11-23 | — | — | EP | disclosed |
| US-20040234634-A1 | Pharmaceutical compositions having appetite suppressant activity | CSIR | 2004-11-25 | — | — | US | disclosed |
| US-20040228935-A1 | Pharmaceutical compositions having appetite suppressant activity | CSIR | 2004-11-18 | — | — | US | disclosed |
| EP-1438965-A1 | Use of extracts from Hoodia gordonii and Hoodia lugardii for the preparation of a medicament for use in the suppression of appetite | CSIR (ZA) | 2004-07-21 | — | — | EP | disclosed |
| US-20030086984-A1 | Pharmaceutical compositions having appetite suppressant activity | CSIR | 2003-05-08 | — | — | US | disclosed |
| US-20020168427-A1 | Pharmaceutical compositions having appetite suppressant activity | CSIR | 2002-11-14 | — | — | US | disclosed |
| EP-1222927-A2 | Pharmaceutical compositions having appetite suppressant activity | CSIR (ZA) | 2002-07-17 | — | — | EP | disclosed |
| EP-1213020-A2 | Pharmaceutical compositions having appetite suppressant activity | CSIR (ZA) | 2002-06-12 | — | — | EP | disclosed |
| US-6376657-B1 | STEROID TRISACCHARIDE EXTRACT OBTAINABLE FROM A PLANT OF THE GENUS TRICHOCAULON OR HOODIA | CSIR (ZA) | 2002-04-23 | — | — | US | disclosed |
| US-5593853-A | DISPLACEMNT, OLIGOMERIZATION, REDUCTION, ALKYLATION, ACTIVATION, PROTECTION, DEPROTECTION, OXIDATION, ALKOLATION, THIOLATION, NITRILATION, SULFITATION, CARBANATION, FRACTIONATION AND TESTING | MARTEK CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0743952-A1 | GENERATION AND SCREENING OF SYNTHETIC DRUG LIBRARIES | MARTEK BIOSCIENCES CORPORATION (US) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021850-A1 | GENERATION AND SCREENING OF SYNTHETIC DRUG LIBRARIES | MARTEK BIOSCIENCES CORPORATION (US) | 1995-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040234634-A1 | Pharmaceutical compositions having appetite suppressant activity | GPR119, TPH1, TRHR | ALDH1A1 1260/4885SMN1; SMN2 4072/4885 |
| US-20020168427-A1 | Pharmaceutical compositions having appetite suppressant activity | GPR119, TPH1, TRHDE | ALDH1A1 1379/4885SMN1; SMN2 4080/4885 |
| US-20030086984-A1 | Pharmaceutical compositions having appetite suppressant activity | TPH1, TRHDE, TRHR | ALDH1A1 1982/4885SMN1; SMN2 4315/4885 |
| US-20040228935-A1 | Pharmaceutical compositions having appetite suppressant activity | GPR119, TPH1, TRHDE | ALDH1A1 1261/4885SMN1; SMN2 4064/4885 |
| US-20060205931-A1 | Pharmaceutical compositions having appetite suppressant activity | GPR119, TPH1, TRHDE | ALDH1A1 1379/4885SMN1; SMN2 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.