Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14882161 | 0.87 | HTT (0.47) | HPGDTSHRCASP6NPC1RAB9A | |
| SCHEMBL256310 | 0.87 | HPGD (0.59) | HPGDTSHRCASP6GAANPC1 | |
| SCHEMBL29717082 | 0.86 | RAB9A (0.57) | HPGDGAANPC1RAB9AHTT | |
| SCHEMBL2104229 | 0.85 | HPGD (0.59) | HPGDTSHRCASP6GAANPC1 | |
| SCHEMBL4243617 | 0.83 | HTT (0.58) | HPGDTSHRCASP6GAANPC1 | |
| SCHEMBL12846473 | 0.83 | HPGD (0.58) | HPGDTSHRGAANPC1RAB9A | |
| SCHEMBL15306495 | 0.81 | HPGD (0.57) | HPGDTSHRNPC1RAB9ANPSR1 | |
| SCHEMBL17774812 | 0.80 | HPGD (0.55) | HPGDTSHRGAANPSR1HTT | |
| SCHEMBL21189588 | 0.80 | SMN1; SMN2 (0.66) | HPGDTSHRNPC1RAB9ANPSR1 | |
| SCHEMBL4154834 | 0.80 | HPGD (0.64) | HPGDTSHRGAAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141694-A1 | PI4KIIIBETA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-07-25 | — | — | WO | disclosed |