SCHEMBL21189759

SCHEMBL21189759

OCC1OC(Sc2cc(Cl)c(F)c(Cl)c2)[C@@H](O)C(n2cc(-c3cscn3)nn2)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 16/20 1.00
LGALS3 P17931 15/20 1.00
LGALS9 O00182 1/20 0.72
LGALS8 O00214 1/20 0.72
LGALS7; LGALS7B P47929 1/20 0.72
LGALS4 P56470 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21175211 1.00 LGALS1 (1.00) LGALS1LGALS3LGALS9LGALS8LGALS7; LGALS7B
SCHEMBL19778324 1.00 LGALS1 (1.00) LGALS1LGALS3LGALS9LGALS8LGALS7; LGALS7B
SCHEMBL21189340 1.00 LGALS1 (1.00) LGALS1LGALS3LGALS9LGALS8LGALS7; LGALS7B
SCHEMBL30023278 0.90 LGALS3 (1.00) LGALS1LGALS3
SCHEMBL21189332 0.90 LGALS3 (1.00) LGALS1LGALS3
SCHEMBL21189339 0.90 LGALS3 (1.00) LGALS1LGALS3
SCHEMBL21175129 0.90 LGALS3 (1.00) LGALS1LGALS3
SCHEMBL19778744 0.90 LGALS3 (1.00) LGALS1LGALS3
SCHEMBL24980690 0.85 LGALS1 (1.00) LGALS1LGALS3LGALS9LGALS8LGALS7; LGALS7B
SCHEMBL22610097 0.85 LGALS1 (0.84) LGALS1LGALS3LGALS9LGALS8LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10988502-B2 Alpha-D-galactoside inhibitors of galectins GALECTO BIOTECH AB (DK) 2021-04-27 US disclosed
US-20190225638-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225638-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS LGALS1, LGALS2, LGALS3 LGALS1 1/4885LGALS3 3/4885LGALS9 6/4885
US-10988502-B2 Alpha-D-galactoside inhibitors of galectins LGALS1, LGALS2, LGALS3 LGALS1 1/4885LGALS3 3/4885LGALS9 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.