Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19934573 | 0.91 | MAPK1 (0.47) | SERPINE1ESR1MAPK1HIF1AAKR1C4 | |
| SCHEMBL21234569 | 0.84 | SERPINE1 (0.70) | SERPINE1ESR1MAPK1HIF1AAKR1C4 | |
| SCHEMBL18746620 | 0.81 | SERPINE1 (0.70) | SERPINE1ESR1MAPK1HIF1AAKR1C4 | |
| SCHEMBL5364253 | 0.81 | CA12 (0.58) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL16055405 | 0.75 | CA12 (0.63) | SERPINE1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9250812 | 0.74 | CES2 (0.47) | SERPINE1MAPK1HIF1ACA12CA1 | |
| SCHEMBL23484207 | 0.73 | SERPINE1 (0.73) | SERPINE1ESR1MAPK1HIF1AAKR1C4 | |
| SCHEMBL1999331 | 0.73 | CA12 (0.60) | ESR1PTPN11CA12CA1CA2 | |
| SCHEMBL5367737 | 0.71 | SERPINE1 (0.44) | SERPINE1ESR1PTPN11CA12CA1 | |
| SCHEMBL2612550 | 0.70 | SMN1; SMN2 (0.48) | SERPINE1MAPK1HIF1AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225774-A1 | MODIFIER FOR RESIN, AND RESIN COMPOSITION USING SAME | ADEKA CORPORATION (JP) | 2019-07-25 | — | — | US | disclosed |