Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246003 | 0.89 | SLC6A3 (0.41) | CES2CES1SERPINE1JMJD6NPC1 | |
| SCHEMBL18786032 | 0.82 | SERPINE1 (0.41) | CES2CES1SERPINE1JMJD6MAPK1 | |
| SCHEMBL19934573 | 0.81 | MAPK1 (0.47) | CES2CES1SERPINE1MAPTSMN1; SMN2 | |
| SCHEMBL1496824 | 0.78 | MAPK1 (0.55) | CES2CES1JMJD6NPC1GAA | |
| SCHEMBL1999331 | 0.77 | CA12 (0.60) | CES2CES1NPC1MAPTCA12 | |
| SCHEMBL9248628 | 0.76 | SLC6A3 (0.45) | SERPINE1JMJD6NPC1GAAMAPT | |
| SCHEMBL1996803 | 0.76 | MAPT (0.58) | CES2JMJD6NPC1GAAMAPT | |
| SCHEMBL9244575 | 0.76 | ADRB2 (0.49) | CES2CES1JMJD6NPC1MAPT | |
| SCHEMBL25478653 | 0.75 | ESR1 (0.57) | SERPINE1JMJD6NPC1GAAMAPT | |
| SCHEMBL7797389 | 0.75 | ELANE (0.47) | SERPINE1JMJD6NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355774-B1 | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS CO LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-4985588-A | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS COMPANY LTD. (JP) | 1991-01-15 | — | — | US | disclosed |