Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.60 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21189934 | 0.86 | F10 (0.77) | F10KLKB1KCNH2F2 | |
| SCHEMBL21189874 | 0.85 | F10 (0.60) | F10KLKB1KCNH2NPC1ALOX15 | |
| SCHEMBL21189829 | 0.84 | F10 (0.54) | F10KLKB1KCNH2NPC1ALOX15 | |
| SCHEMBL2431818 | 0.76 | F10 (0.87) | F10KLKB1KCNH2 | |
| SCHEMBL2431134 | 0.75 | F10 (1.00) | F10KLKB1KCNH2F2 | |
| SCHEMBL2436147 | 0.73 | F10 (0.72) | F10KLKB1KCNH2 | |
| SCHEMBL12326434 | 0.73 | F10 (0.79) | F10KLKB1KCNH2 | |
| SCHEMBL21319613 | 0.73 | F10 (0.76) | F10KLKB1KCNH2 | |
| SCHEMBL19129013 | 0.73 | F10 (0.81) | F10KLKB1KCNH2F2 | |
| SCHEMBL21319602 | 0.72 | F10 (0.58) | F10KLKB1KCNH2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143273-A1 | NOVEL AMIDINE INHIBITORS OF FACTOR XA | ООО "ФармаДиол" | 2019-07-25 | — | — | WO | disclosed |