Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431818 | 0.88 | F10 (0.87) | F10KCNH2KLKB1 | |
| SCHEMBL2431134 | 0.87 | F10 (1.00) | F10KCNH2KLKB1F2 | |
| SCHEMBL21189873 | 0.86 | F10 (0.60) | F10KCNH2KLKB1F2 | |
| SCHEMBL19129013 | 0.84 | F10 (0.81) | F10KCNH2KLKB1F2 | |
| SCHEMBL2439114 | 0.84 | F10 (0.78) | F10KCNH2 | |
| SCHEMBL2438967 | 0.83 | F10 (0.79) | F10KCNH2KLKB1F2 | |
| SCHEMBL21189827 | 0.83 | F10 (0.70) | F10KCNH2KLKB1F2 | |
| SCHEMBL6111211 | 0.80 | F10 (0.74) | F10KCNH2KLKB1 | |
| SCHEMBL12325912 | 0.80 | F10 (0.86) | F10KCNH2KLKB1F2 | |
| SCHEMBL6107976 | 0.79 | F10 (0.86) | F10KCNH2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143273-A1 | NOVEL AMIDINE INHIBITORS OF FACTOR XA | ООО "ФармаДиол" | 2019-07-25 | — | — | WO | disclosed |