Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 5/20 | 0.31 |
| ▸ | HTR2B | P41595 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.30 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19931197 | 0.82 | P2RX3 (0.34) | HTR2CHTR2BHTR2ACNR2CNR1 | |
| SCHEMBL21190751 | 0.82 | BRD4 (0.45) | HTR2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21190757 | 0.81 | AAK1 (0.34) | EGFR | |
| SCHEMBL16650483 | 0.81 | BRD4 (0.46) | CNR2CNR1 | |
| SCHEMBL984993 | 0.80 | CNR2 (0.35) | HTR2CHTR2BHTR2APDE4BCNR2 | |
| SCHEMBL25964263 | 0.80 | EGFR (0.40) | EGFR | |
| SCHEMBL983516 | 0.79 | HTR2C (0.47) | HTR2CHTR2BHTR2APDE4BPDE4A | |
| SCHEMBL20154965 | 0.79 | HTR2C (0.36) | HTR2CHTR2BHTR2ACNR2CNR1 | |
| SCHEMBL21191010 | 0.79 | POLB (0.35) | PDE4BPDE4APDE4CPDE4DC5AR1 | |
| SCHEMBL1438795 | 0.78 | LPL (0.35) | HTR2CHTR2BHTR2APDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |