SCHEMBL2120071

SCHEMBL2120071

C=C(C)C(=O)OCCCOCOCC

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.65
TSHR P16473 7/20 0.58
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 7/20 0.38
CES2 O00748 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120122 0.96 THRB (0.65) THRBTSHRPOLBAPEX1HTT
SCHEMBL234130 0.91 THRB (0.78) THRBTSHRPOLBAPEX1HTT
SCHEMBL283313 0.89 THRB (0.81) THRBTSHRPOLBAPEX1HTT
SCHEMBL2118746 0.87 THRB (0.79) THRBTSHRPOLBAPEX1HTT
SCHEMBL1170964 0.87 THRB (0.78) THRBTSHRPOLBAPEX1HTT
SCHEMBL9594035 0.86 THRB (0.70) THRBTSHRPOLBAPEX1HTT
SCHEMBL29626882 0.86 THRB (0.82) THRBTSHRPOLBAPEX1HTT
SCHEMBL3794443 0.85 THRB (0.75) THRBTSHRPOLBAPEX1HTT
SCHEMBL3788969 0.85 THRB (0.75) THRBTSHRPOLBAPEX1HTT
SCHEMBL8850646 0.85 THRB (0.75) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318824-B2 Hydrophilic polyolefin sintered body ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-11-27 US disclosed
US-20120095121-A1 HYDROPHILIC POLYOLEFIN SINTERED BODY ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-04-19 US disclosed
EP-2174975-A1 HYDROPHILIC POLYOLEFIN SINTERED BODY Asahi Kasei Chemicals Corporation (JP) 2010-04-14 EP disclosed