Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2165271 | 0.82 | ACP3 (0.47) | LMNAHIF1AKDM4EPTGS1MAPT | |
| SCHEMBL8579553 | 0.81 | PTGS1 (0.59) | CPN1CPB2LMNAHIF1AKDM4E | |
| SCHEMBL360725 | 0.81 | PTGS1 (0.59) | CPN1CPB2LMNAHIF1AKDM4E | |
| SCHEMBL180160 | 0.81 | LMNA (0.54) | LMNAHIF1AKDM4EPTGS2MAPK1 | |
| SCHEMBL10024370 | 0.81 | LMNA (0.54) | LMNAHIF1AKDM4EPTGS2MAPK1 | |
| SCHEMBL7525226 | 0.81 | LMNA (0.54) | LMNAHIF1AKDM4EPTGS2MAPK1 | |
| Hydrochloric Acid SCHEMBL1177638 | 0.80 | PTGS1 (0.57) | CPN1CPB2LMNAHIF1AKDM4E | |
| SCHEMBL21200033 | 0.79 | CPN1 (0.44) | CPN1CPB2LMNAKDM4EMAPT | |
| SCHEMBL7080114 | 0.77 | CPN1 (0.61) | CPN1CPB2LMNAHIF1AKDM4E | |
| SCHEMBL1095105 | 0.77 | LMNA (0.61) | CPN1CPB2LMNAKDM4EPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743063-A1 | INHIBITORS OF CBL-B AND METHODS OF USE THEREOF | Nurix Therapeutics, Inc. (US) | 2020-12-02 | — | — | EP | disclosed |
| WO-2019148005-A1 | INHIBITORS OF CBL-B AND METHODS OF USE THEREOF | NURIX THERAPEUTICS, INC. (US) | 2019-08-01 | — | — | WO | disclosed |