Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17401223 | 0.84 | HTR2A (0.47) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL17401224 | 0.79 | HTR2A (0.47) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL21891271 | 0.69 | DRD2 (0.41) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL19766703 | 0.69 | CA1 (0.38) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL21192353 | 0.69 | CA1 (0.38) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL18287892 | 0.68 | HTR2A (0.45) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL16671856 | 0.67 | MGLL (0.51) | CA1CA2CA7CA9CA12 | |
| SCHEMBL16577518 | 0.67 | ABCB1 (0.57) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL27425024 | 0.67 | KDM4E (0.44) | HTR2ACA1CA2CA7CA9 | |
| SCHEMBL11488229 | 0.66 | MAPT (0.54) | CA1CA2CA7CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364249-B2 | Azatriangulenium salts as PET-quenched fluorescent probes | KOBENHAVNS UNIVERSITET (DK) | 2019-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364249-B2 | Azatriangulenium salts as PET-quenched fluorescent probes | SLC7A5, SLC16A7, KCNN1 | HTR2A 3910/4885CA1 110/4885CA2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.