SCHEMBL21202148

SCHEMBL21202148

CCCCCOC(=O)C(CCC#N)C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSS P25774 3/20 0.40
CTSK P43235 3/20 0.40
NAAA Q02083 1/20 0.36
TSHR P16473 5/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
EPHX1 P07099 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.33
HCAR2 Q8TDS4 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
RAD52 P43351 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20528166 0.87 TSHR (0.41) NAAATSHRTP53CYP3A4MAPK1
SCHEMBL21475351 0.86 CTSS (0.32) CTSSCTSKMEN1KMT2A
SCHEMBL21202146 0.86 CTSS (0.32) CTSSCTSKMEN1KMT2A
SCHEMBL21202161 0.86 CTSS (0.32) CTSSCTSKMEN1KMT2A
SCHEMBL20528141 0.85 NAAA (0.43) NAAATSHREPHX1ALDH1A1LMNA
SCHEMBL19105332 0.85 TSHR (0.45) NAAATSHRMAPK1EPHX1ALDH1A1
SCHEMBL21480847 0.84 NAAA (0.42) NAAATSHRMAPK1EPHX1ZDHHC20
SCHEMBL21485102 0.84 NAAA (0.42) NAAATSHRMAPK1EPHX1ZDHHC20
SCHEMBL21202147 0.83 ZDHHC7 (0.44) NAAATSHREPHX1ZDHHC20HCAR2
SCHEMBL21475350 0.83 ZDHHC7 (0.44) NAAATSHREPHX1ZDHHC20HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10367228-B2 Diester-based polymer electrolytes for high voltage lithium ion batteries SEEO, INC. (US) 2019-07-30 US disclosed