Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | VNN1 | O95497 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638075 | 0.89 | LTA4H (0.61) | LTA4HCYP1A2CYP2D6HDAC3HDAC1 | |
| SCHEMBL22190975 | 0.87 | HDAC1 (0.61) | LTA4HCYP1A2CYP2D6HDAC3HDAC1 | |
| SCHEMBL23094488 | 0.84 | HDAC3 (0.62) | LTA4HCYP1A2CYP2D6HDAC3HDAC1 | |
| SCHEMBL21381213 | 0.83 | HDAC3 (0.61) | LTA4HCYP1A2CYP2D6HDAC3HDAC1 | |
| SCHEMBL30074037 | 0.82 | FABP1 (0.71) | LTA4HCYP1A2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL3933500 | 0.82 | FABP1 (0.71) | LTA4HCYP1A2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL5596295 | 0.81 | LTA4H (0.53) | LTA4HCYP1A2CYP2D6HDAC3HDAC1 | |
| SCHEMBL1763523 | 0.80 | LTA4H (0.56) | LTA4HCYP1A2CYP2D6HDAC3HDAC1 | |
| SCHEMBL19779254 | 0.80 | VNN1 (0.77) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL5605047 | 0.80 | LTA4H (0.82) | LTA4HCYP1A2CYP2D6ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095011-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095011-A1 | NOVEL COMPOUNDS | C1R, TBXA2R, F12 | LTA4H 840/4885CYP1A2 64/4885CYP2D6 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.