Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21203260 | 0.94 | MAOB (0.60) | KDM4EMAOBBCHEACHEESR1 | |
| SCHEMBL10021700 | 0.92 | MAOB (0.59) | LTA4HKDM4EPOLBGAABACE1 | |
| SCHEMBL10021719 | 0.88 | KDM4E (0.65) | KDM4EPOLBGAABACE1MAOB | |
| SCHEMBL10021699 | 0.86 | MAOB (0.60) | KDM4EMAOBBCHEACHEHRH3 | |
| SCHEMBL15996545 | 0.86 | MAOB (0.51) | KDM4EPOLBGAABACE1MAOB | |
| SCHEMBL10021702 | 0.81 | KEAP1 (0.57) | KDM4EPOLBMAOBHSP90AA1ALDH1A1 | |
| SCHEMBL4965868 | 0.80 | BACE1 (0.62) | LTA4HKDM4EPOLBGAABACE1 | |
| SCHEMBL29417616 | 0.80 | BACE1 (0.62) | LTA4HKDM4EPOLBGAABACE1 | |
| SCHEMBL21203245 | 0.79 | KDM4E (0.58) | KDM4EMAOBESR1HRH3KMT2A | |
| SCHEMBL1283353 | 0.79 | LTA4H (0.61) | LTA4HKDM4EPOLBGAABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606021-B1 | 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS | UNIV TOKYO (JP) | 2019-07-31 | — | — | EP | disclosed |