Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11675266 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL3209197 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL62978 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL6939763 | 0.97 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Ammonia Solution, Strong SCHEMBL6935288 | 0.97 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL11863762 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL5915259 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL11676491 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL11072538 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL8875 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634145-A1 | METHOD FOR SEPARATING A MIXED HYDROCARBON STREAM COMPRISING N-BUTENES USING A DIVIDING WALL DISTILLATION COLUMN MAKING N-BUTENES AND SEPARATION THEREOF | BASF SE (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024105087-A1 | METHOD FOR SEPARATING A MIXED HYDROCARBON STREAM COMPRISING N-BUTENES USING A DIVIDING WALL DISTILLATION COLUMN MAKING N-BUTENES AND SEPARATION THEREOF | BASF SE (DE) | 2024-05-23 | — | — | WO | disclosed |
| EP-3536678-B1 | PROCESS FOR PRODUCING PROPYLENE AND ALKYLATE | LYONDELL CHEMICAL TECH LP (US) | 2020-10-21 | — | — | EP | disclosed |
| US-10737992-B2 | Methods of forming propylene and alkylate | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190276378-A1 | METHODS OF FORMING PROPYLENE AND ALKYLATE | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2019-09-12 | — | — | US | disclosed |
| EP-3536678-A1 | PROCESS FOR PRODUCING PROPYLENE AND ALKYLATE | Lyondell Chemical Technology, L.P. (US) | 2019-09-11 | — | — | EP | disclosed |
| US-8395005-B2 | Production of 1-butene and propylene from ethylene | EQUISTAR CHEMICALS, LP (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120095275-A1 | Production of 1-Butene and Propylene From Ethylene | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2012051427-A1 | PRODUCTION OF 1-BUTENE AND PROPYLENE FROM ETHYLENE | EQUISTAR CHEMICALS, LP (US) | 2012-04-19 | — | — | WO | disclosed |
| US-20090269645-A1 | POLYMER, POLYMER ELECTROLYTE AND FUEL CELL USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-1721922-A1 | METHOD FOR PRODUCING POLYMER COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-11-15 | — | — | EP | disclosed |
| EP-0655071-B1 | METHOD OF PREPARING 1-METHYL-3-KETO-$g(D)?1,4 -STEROIDS | SCHERING AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| US-5523428-A | Process for the production of 1-methyl-3-keto-Δ1,4 steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0655071-A1 | METHOD OF PREPARING 1-METHYL-3-KETO--g(D)?1,4 -STEROIDS. | SCHERING AG (DE) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004553-A1 | METHOD OF PREPARING 1-METHYL-3-KETO-Δ1,4-STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10737992-B2 | Methods of forming propylene and alkylate | APEX1, ALKBH3, PNN | ACHE 1536/4885TDP1 247/4885CYP3A4 150/4885 |
| US-20190276378-A1 | METHODS OF FORMING PROPYLENE AND ALKYLATE | APEX1, ALKBH3, PNN | ACHE 1536/4885TDP1 247/4885CYP3A4 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.