Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11675266 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL3209197 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL2120376 | 1.00 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL6939763 | 0.97 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Ammonia Solution, Strong SCHEMBL6935288 | 0.97 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL11863762 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL5915259 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL11676491 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL11072538 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL8875 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2076 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059975-A | Eight-membered ring condensed boron dipyrrole compound and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2026-05-19 | — | — | CN | claimed |
| CN-119191946-B | Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide | 南京工业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-116969864-B | Synthesis method of aromatic sulfonyl fluoride compound | 江南大学 | 2025-06-24 | — | — | CN | claimed |
| US-20250197356-A1 | METHOD FOR SYNTHESIZING NUCIFERINE OR DERIVATIVE THEREOF, DERIVATIVE OF NUCIFERINE AND USE THEREOF | HUAQIAO UNIVERSITY (CN) | 2025-06-19 | — | — | US | claimed |
| CN-120157192-A | Ni (OH) synthesized by taking organic heterocycle as template2Ultrathin nanosheets and preparation method thereof | 黄冈师范学院 | 2025-06-17 | — | — | CN | claimed |
| CN-120157616-A | Method for synthesizing full-carbon quaternary carbon stereogenic center compound by nickel-catalyzed asymmetric amino group | 浙江大学 | 2025-06-17 | — | — | CN | claimed |
| CN-116947865-B | Synthesis method of risperidone intermediate and Li Sipu-blue intermediate | 扬州联澳生物医药有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120081813-A | Two-photon initiator, preparation method and application | 西安江大微纳材料科技有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-115651017-B | Method for selectively preparing benzyl or alkyl phosphine oxide compound based on benzyl thioether derivative | 中南大学 | 2025-05-27 | — | — | CN | claimed |
| CN-120025238-A | Method for photochemically synthesizing alpha, beta-unsaturated ketone | 南京师范大学 | 2025-05-23 | — | — | CN | claimed |
| EP-0470795-B2 | Process for the manufacture of nitriles | AVECIA LTD (GB) | 2001-02-21 | — | — | EP | claimed |
| EP-0455423-B1 | Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl) benzenes | MERCK & CO INC (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0532515-B1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER (US) | 1996-10-23 | — | — | EP | claimed |
| EP-0619806-B1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER (US) | 1996-01-03 | — | — | EP | claimed |
| US-5412102-A | Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid | SYNTEX (U.S.A.) INC. (US) | 1995-05-02 | — | — | US | claimed |
| EP-0470795-B1 | Process for the manufacture of nitriles | ZENECA LTD (GB) | 1995-01-25 | — | — | EP | claimed |
| EP-0470795-A1 | Process for the manufacture of nitriles | ZENECA LIMITED (GB) | 1992-02-12 | — | — | EP | claimed |
| EP-0455423-A2 | Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl) benzenes | MERCK & CO. INC. (US) | 1991-11-06 | — | — | EP | claimed |
| US-5039814-A | Chemical intermediates for angiotensin antagonist | MERCK & CO., INC. (US) | 1991-08-13 | — | — | US | claimed |
| US-4620025-A | NICKEL COMPLEX CATALYSTS | MERCK & CO., INC. (US) | 1986-10-28 | — | — | US | claimed |