Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530040 | 0.78 | CASP3 (0.43) | DPP4DPP7 | |
| SCHEMBL20912879 | 0.78 | CASP3 (0.43) | DPP4DPP7 | |
| SCHEMBL1530042 | 0.78 | CASP3 (0.43) | DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL1641409 | 0.77 | DPP4 (0.43) | DPP4DPP7DPP8 | |
| SCHEMBL20925878 | 0.76 | DPP4 (0.42) | DPP4DPP7 | |
| SCHEMBL29478387 | 0.70 | DPP4 (0.59) | DPP4DPP7DPP8PIN1KCNH2 | |
| SCHEMBL29478415 | 0.70 | DPP4 (0.59) | DPP4DPP7DPP8PIN1KCNH2 | |
| SCHEMBL2027308 | 0.70 | DPP4 (0.59) | DPP4DPP7DPP8PIN1KCNH2 | |
| SCHEMBL2031965 | 0.70 | DPP4 (0.59) | DPP4DPP7DPP8PIN1KCNH2 | |
| SCHEMBL2027312 | 0.70 | DPP4 (0.59) | DPP4DPP7DPP8PIN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654868-B2 | Dihydropyrazole azepine compound serving as Akt inhibitor | Harbin Zhenbao Pharmaceutical Co., Ltd. (CN) | 2020-05-19 | — | — | US | disclosed |
| US-20190233434-A1 | DIHYDROPYRAZOLE AZEPINE COMPOUND SERVING AS AKT INHIBITOR | Harbin Zhenbao Pharmaceutical Co., Ltd. (CN) | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654868-B2 | Dihydropyrazole azepine compound serving as Akt inhibitor | AKT3, AKT2, AKT1 | DPP4 938/4885DPP7 560/4885DAO 3017/4885 |
| US-20190233434-A1 | DIHYDROPYRAZOLE AZEPINE COMPOUND SERVING AS AKT INHIBITOR | AKT3, AKT2, AKT1 | DPP4 938/4885DPP7 560/4885DAO 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.