Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530042 | 0.86 | CASP3 (0.43) | DPP4CASP3ACHEDPP7ALDH1A1 | |
| SCHEMBL20912879 | 0.86 | CASP3 (0.43) | DPP4CASP3ACHEDPP7ALDH1A1 | |
| SCHEMBL1530040 | 0.86 | CASP3 (0.43) | DPP4CASP3ACHEDPP7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1641409 | 0.85 | DPP4 (0.43) | DPP4CASP3ACHEDPP7ALDH1A1 | |
| SCHEMBL4780119 | 0.82 | CASP3 (0.55) | CASP3ACHEALDH1A1POLB | |
| SCHEMBL4782347 | 0.82 | CASP3 (0.55) | CASP3ACHEALDH1A1POLB | |
| SCHEMBL4782342 | 0.82 | CASP3 (0.55) | CASP3ACHEALDH1A1POLB | |
| SCHEMBL13919613 | 0.80 | POLB (0.51) | CASP3ALDH1A1POLBSMN1; SMN2CA1 | |
| SCHEMBL7614758 | 0.78 | GLS (0.55) | CASP3ALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL21206409 | 0.76 | DPP4 (0.43) | DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473628-A1 | DIHYDROPYRAZOLE AZEPINE COMPOUND SERVING AS AKT INHIBITOR | Medshine Discovery Inc. (CN) | 2019-04-24 | — | — | EP | disclosed |