Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20230973 | 0.93 | HRH3 (0.54) | HRH3 | |
| SCHEMBL20234779 | 0.91 | HRH3 (0.47) | HRH3KDM4E | |
| SCHEMBL20230970 | 0.84 | KCNA5 (0.59) | KDM4EALDH1A1TDP1 | |
| SCHEMBL20234777 | 0.83 | KCNA5 (0.58) | HRH3KDM4EALDH1A1 | |
| SCHEMBL20234801 | 0.81 | KCNA5 (0.47) | KMT2AHRH3MEN1KDM4EALDH1A1 | |
| SCHEMBL20325308 | 0.81 | LTA4H (0.53) | HRH3KDM4EALDH1A1 | |
| SCHEMBL20234772 | 0.80 | KCNA5 (0.60) | HRH3ALDH1A1 | |
| SCHEMBL9968680 | 0.80 | LTA4H (0.66) | KMT2AHRH3MEN1KCNH2 | |
| SCHEMBL21026132 | 0.79 | HRH3 (0.50) | KMT2AHRH3KDM4EKCNH2 | |
| SCHEMBL20329995 | 0.79 | KMT2A (0.48) | KMT2AHRH3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148055-A9 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE | YALE UNIVERSITY (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019148055-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE | YALE UNIVERSITY (US) | 2019-08-01 | — | — | WO | disclosed |