SCHEMBL21208288

SCHEMBL21208288

CC1C(c2ccccc2)C(c2ccccc2)C2OC2C(c2ccccc2)C1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
TSHR P16473 1/20 0.34
CYP2C19 P33261 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SLC6A3 Q01959 2/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
RAB9A P51151 1/20 0.33
EPHX1 P07099 3/20 0.32
HDAC4 P56524 2/20 0.32
HTR1A P08908 1/20 0.32
POLB P06746 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30504112 0.85 MAOA (0.41) MAOAMAOBTSHRCYP2C19MEN1
SCHEMBL30311870 0.80 MAOA (0.41) MAOAMAOBTSHRCYP2C19MEN1
SCHEMBL30312236 0.80 MAOA (0.41) MAOAMAOBTSHRCYP2C19MEN1
SCHEMBL30312066 0.80 MAOA (0.41) MAOAMAOBTSHRCYP2C19MEN1
SCHEMBL8435497 0.75 MAOA (0.41) MAOAMAOBTSHRCYP2C19MEN1
SCHEMBL25332884 0.71 MAOA (0.34) MAOAMAOBHDAC4POLBHDAC3
SCHEMBL21399752 0.71 POLB (0.39) MAOAMAOBPOLB
SCHEMBL19366234 0.70 SLC6A2 (0.39) MAOAMAOBMEN1KMT2ASLC6A3
SCHEMBL8435493 0.69 MAOA (0.38) MAOAMAOBTSHRCYP2C19MEN1
SCHEMBL19366232 0.68 HDAC4 (0.50) MAOAMAOBMEN1KMT2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190233282-A1 CARBON-BASED HYDROGEN STORAGE MATERIAL HAVING AUTOCATALYTIC CAPABILITY, PRODUCTION METHOD THEREOF, AND HYDROGEN ADSORBING - STORING METHOD, HYDROGEN RELEASING METHOD, AND HYDROGEN ADSORPTION - STORAGE DEVICE USING THEREOF OSAKA UNIVERSITY (JP) 2019-08-01 US disclosed