Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.51 |
| ▸ | CHUK | O15111 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21208536 | 0.83 | IKBKB (0.54) | IKBKBCHUKHSD17B10KDM4EHPGD | |
| SCHEMBL21208493 | 0.81 | KDM4E (0.48) | IKBKBCHUKHSD17B10KDM4EHPGD | |
| SCHEMBL21208516 | 0.81 | KDM4E (0.45) | IKBKBCHUKKDM4ECASP1CASP7 | |
| SCHEMBL21208501 | 0.80 | KDM4E (0.52) | IKBKBCHUKHSD17B10KDM4EHPGD | |
| SCHEMBL21208537 | 0.71 | EGFR (0.40) | HSD17B10KDM4EHPGDCASP1CASP7 | |
| SCHEMBL21208545 | 0.71 | HRH4 (0.54) | HSD17B10ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL21208465 | 0.70 | TYMS (0.47) | HSD17B10KDM4EHPGDCASP1CASP7 | |
| SCHEMBL21208535 | 0.70 | EGFR (0.39) | HSD17B10KDM4EHPGDCASP1CASP7 | |
| SCHEMBL18057521 | 0.70 | POLR1A (0.40) | KDM4EHPGDALDH1A1KMT2AMAPT | |
| SCHEMBL19365198 | 0.69 | KDM4E (0.55) | IKBKBCHUKHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317120-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2021-10-14 | — | — | US | disclosed |
| US-10975076-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190233422-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975076-B2 | Compositions, uses and methods for making them | BAX, CASP3, CASP7 | IKBKB 853/4885CHUK 368/4885HSD17B10 1104/4885 |
| US-20190233422-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, BCL2 | IKBKB 1148/4885CHUK 608/4885HSD17B10 1289/4885 |
| US-20210317120-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, CASP7 | IKBKB 998/4885CHUK 495/4885HSD17B10 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.