Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.67 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.67 |
| ▸ | AHCY | P23526 | 11/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.63 |
| ▸ | PI4KA | P42356 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25390247 | 0.91 | AHCY (0.66) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL4650654 | 0.91 | AHCY (0.66) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL26239612 | 0.91 | AHCY (0.66) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL25390909 | 0.91 | AHCY (0.66) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL8990546 | 0.91 | AHCY (0.66) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL397800 | 0.91 | AHCY (0.68) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL31680251 | 0.91 | AHCY (0.68) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL6671788 | 0.90 | AHCY (0.67) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL7803295 | 0.90 | AHCY (0.67) | PRMT5WDR77AHCYADORA2AADORA2B | |
| SCHEMBL2040666 | 0.89 | PRMT5 (0.66) | PRMT5WDR77AHCYADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122095093-A | RNAi agents for inhibiting expression of inhibin subunit beta E (INHBE), pharmaceutical compositions and methods of use | — | 2026-05-26 | — | — | CN | claimed |
| CN-110832077-B | RNAi agents for inhibiting alpha-ENaC expression and methods of use | 箭头药业股份有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-110234326-B | Compositions and methods for inhibiting factor XII gene expression | 箭头药业股份有限公司 | 2024-11-12 | — | — | CN | claimed |
| WO-2024086633-A1 | RNAI AGENTS FOR INHIBITING EXPRESSION OF DM1 PROTEIN KINASE (DMPK) COMPOSITIONS THEREOF, AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2024-04-25 | — | — | WO | claimed |
| CN-111343994-B | RNAi agents and compositions for inhibiting expression of angiopoietin-like 3 (ANGPTL 3) and methods of use | 箭头药业股份有限公司 | 2023-11-21 | — | — | CN | claimed |
| EP-3350333-A2 | POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION | ModernaTX, Inc. (US) | 2018-07-25 | — | — | EP | claimed |
| WO-2017049275-A2 | POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION | MODERNA THERAPEUTICS, INC. (US) | 2017-03-23 | — | — | WO | claimed |
| WO-2017049286-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | MODERNA THERAPEUTICS, INC. (US) | 2017-03-23 | — | — | WO | claimed |
| US-8889645-B2 | Nucleic acid modulators of glycoprotein VI | REGADO BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | claimed |
| US-20140128587-A1 | NUCLEIC ACID MODULATORS OF GLYCOPROTEIN VI | REGADO BIOSCIENCES, INC. (US) | 2014-05-08 | — | — | US | claimed |
| EP-1485395-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | Biota, Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003072757-A9 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA INC (US) | 2004-10-21 | — | — | WO | claimed |
| EP-1392375-A2 | COMPOSITION AND USE OF SUBSTANCES FOR STABILISING AMINO ACIDS CONTAINING SULPHUR | WIELAND, Heinrich (DE) | 2004-03-03 | — | — | EP | claimed |
| WO-2003072757-A2 | NUCLEOTIDE MIMICS AND THEIR PRODRUGS | BIOTA, INC. (US) | 2003-09-04 | — | — | WO | claimed |
| WO-2002094248-A2 | COMPOSITION AND USE OF SUBSTANCES FOR STABILISING AMINO ACIDS CONTAINING SULPHUR AND/OR FOR INHIBITING THE CONTINUOUS FORMATION OF AMINO ACIDS CONTAINING SULPHUR IN A BLOOD SAMPLE | WIELAND HEINRICH (DE) | 2002-11-28 | — | — | WO | claimed |
| CN-1285843-A | Compound (I) | GLAXO GROUP LTD (GB) | 2001-02-28 | — | — | CN | claimed |
| CN-1045791-A | Use the cooperative compositions HIV inhibiting of nucleoside derivates | ONCOGEN (US) | 1990-10-03 | — | — | CN | claimed |
| CN-122095093-A | RNAi agents for inhibiting expression of inhibin subunit beta E (INHBE), pharmaceutical compositions and methods of use | — | 2026-05-26 | — | — | CN | disclosed |
| CN-1023561-C | Process for preparing cryptoclindamycin/adenosine derivatives | MERRELL DOW PHARMA (US) | 1994-01-19 | — | — | CN | disclosed |
| CN-1033632-A | NOVEL ARISTEROMYCIN/ADENOSINE DERIVATIVES | MERRELL DOW PHARMA (US) | 1989-07-05 | — | — | CN | disclosed |