Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.68 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684008 | 0.95 | PPARA (0.62) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL21991231 | 0.95 | PPARA (0.62) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL4755987 | 0.92 | PPARA (0.72) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL10733316 | 0.90 | PPARA (0.53) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL29024630 | 0.89 | PPARA (0.56) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL29024473 | 0.89 | PPARA (0.56) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11643674 | 0.87 | PPARA (0.70) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL31084129 | 0.87 | PPARA (0.69) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL21992527 | 0.87 | PPARA (0.57) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| Dulofibrate SCHEMBL2110601 | 0.85 | PPARA (0.68) | PPARACYP1A2CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220031643-A1 | USE OF GEMFIBROZIL AND DERIVATIVE THEREOF FOR TREATMENT AND/OR PREVENTION OF NEURODEGENERATIVE DISEASE | KUNMING INSTITUTE OF ZOOLOGY CHINESE ACADEMY OF SCIENCES (CN) | 2022-02-03 | — | — | US | disclosed |
| US-10800733-B2 | Acetophenone compound, preparation method therefor, and application thereof in blood lipid regulation | SHANGHAI BIOENERGY MEDICINE SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2020-10-13 | — | — | US | disclosed |
| WO-2020082941-A1 | USE OF GEMIFIBROZIL AND DERIVATIVE THEREOF FOR TREATMENT AND/OR PREVENTION OF NEURODEGENERATIVE DISEASE | 中国科学院昆明动物研究所 | 2020-04-30 | — | — | WO | disclosed |
| US-20190292137-A1 | Acetophenone Compound, Preparation Method Therefor, And Application Thereof In Blood Lipid Regulation | SHANGHAI BIOENERGY MEDICINE SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2019-09-26 | — | — | US | disclosed |
| US-8871894-B2 | Production method of polyhydroxyimide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| CN-102459416-B | Process for production of polyhydroxyimide | NISSAN CHEMICAL IND LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-102459416-A | Method for producing polyhydroxyimide | NISSAN CHEMICAL IND LTD | 2012-05-16 | — | — | CN | disclosed |
| US-20120094232-A1 | PRODUCTION METHOD OF POLYHYDROXYIMIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-5674747-A | GENETIC ENGINEERED BACULOVIRUS HAVING SPECIFIC NULEOTIDE SEQUENCE FOR JUVENILE HORMONE ESTERASE OR MUTANT CAPABLE OF DEGRADING INSECT JUVENILE HORMONE, CODES FOR SUBSTITUTED AMINOACID RESIDUE AT LYSINE POSITIN 29 AND 522, OR SERINE 201 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-10-07 | — | — | US | disclosed |
| US-5643776-A | INSECTICIDES, GENETIC ENGINEERING AND ENZYMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0654076-A1 | INSECT DIAGNOSTIC AND CONTROL COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003588-A1 | INSECT DIAGNOSTIC AND CONTROL COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800733-B2 | Acetophenone compound, preparation method therefor, and application thereof in blood lipid regulation | FAR1, CYP46A1, CYP51A1 | PPARA 243/4885CYP1A2 647/4885CYP3A4 182/4885 |
| US-20220031643-A1 | USE OF GEMFIBROZIL AND DERIVATIVE THEREOF FOR TREATMENT AND/OR PREVENTION OF NEURODEGENERATIVE DISEASE | HTT, GBA1, SMN1; SMN2 | PPARA 169/4885CYP1A2 3615/4885CYP3A4 2041/4885 |
| US-20190292137-A1 | Acetophenone Compound, Preparation Method Therefor, And Application Thereof In Blood Lipid Regulation | FAR1, CYP46A1, CYP51A1 | PPARA 243/4885CYP1A2 647/4885CYP3A4 182/4885 |
| US-20120094232-A1 | PRODUCTION METHOD OF POLYHYDROXYIMIDE | GRHPR, MRPL21, F12 | PPARA 4545/4885CYP1A2 2717/4885CYP3A4 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.