Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21214748 | 1.00 | DNM1 (0.36) | DNM1GBA1ALDH1A1TDP1THRB | |
| SCHEMBL20376199 | 0.94 | DNM1 (0.34) | DNM1GBA1 | |
| SCHEMBL22871230 | 0.91 | DNM1 (0.39) | DNM1GBA1ALDH1A1TDP1 | |
| SCHEMBL26323586 | 0.85 | DNM1 (0.44) | DNM1GBA1 | |
| SCHEMBL22400190 | 0.83 | DNM1 (0.41) | DNM1GBA1THRBTSHR | |
| SCHEMBL21911258 | 0.83 | DNM1 (0.41) | DNM1GBA1THRBTSHR | |
| SCHEMBL21725511 | 0.83 | DNM1 (0.41) | DNM1GBA1THRBTSHR | |
| SCHEMBL21912150 | 0.83 | DNM1 (0.41) | DNM1GBA1THRBTSHR | |
| SCHEMBL13285534 | 0.81 | CPN1 (0.38) | — | |
| SCHEMBL11926006 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019147862-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. (US) | 2019-08-01 | — | — | WO | disclosed |