Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725511 | 0.98 | DNM1 (0.41) | DNM1LMNAGBA1 | |
| SCHEMBL22400190 | 0.98 | DNM1 (0.41) | DNM1LMNAGBA1 | |
| SCHEMBL21912150 | 0.98 | DNM1 (0.41) | DNM1LMNAGBA1 | |
| SCHEMBL21911258 | 0.98 | DNM1 (0.41) | DNM1LMNAGBA1 | |
| SCHEMBL22871230 | 0.94 | DNM1 (0.39) | DNM1GBA1 | |
| SCHEMBL24106671 | 0.90 | DNM1 (0.38) | DNM1LMNA | |
| SCHEMBL20376199 | 0.88 | DNM1 (0.34) | DNM1LMNAGBA1OPRM1 | |
| SCHEMBL21214747 | 0.85 | DNM1 (0.36) | DNM1GBA1 | |
| SCHEMBL21214748 | 0.85 | DNM1 (0.36) | DNM1GBA1 | |
| SCHEMBL20804074 | 0.85 | DNM1 (0.39) | DNM1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279014-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279014-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | HAVCR2, EIF2AK2, OAT | DNM1 934/4885LMNA 1800/4885GBA1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.