SCHEMBL21215965

SCHEMBL21215965

C=CC(C)(CC)c1ccc(Cc2ccc(-c3ccc(Cc4ccc(N5C(=O)C6C(C5=O)C5C(=O)N(C(C)(CC)CC)C(=O)C65)cc4)cc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
TRIP13 Q15645 1/20 0.33
LMNA P02545 2/20 0.31
KCNH2 Q12809 1/20 0.31
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21215696 0.85 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1HPGDHTTTRIP13
SCHEMBL21215977 0.79 KMT2A (0.33) SMN1; SMN2ALDH1A1HPGD
SCHEMBL21215699 0.75 KMT2A (0.35) SMN1; SMN2ALDH1A1HPGDHTT
SCHEMBL21216007 0.70 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1HTTLMNAFAAH
SCHEMBL21215972 0.69 HSP90AA1 (0.33) SMN1; SMN2
SCHEMBL21658073 0.67 ALDH1A1 (0.39) ALDH1A1HTT
SCHEMBL21215975 0.64 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1HPGDHTTLMNA
SCHEMBL12812243 0.63 STAT3 (0.42) ALDH1A1HPGDRAB9A
SCHEMBL14494737 0.62 KMT2A (0.37) SMN1; SMN2ALDH1A1RAB9A
SCHEMBL21577183 0.62 MGLL (0.50) SMN1; SMN2ALDH1A1HPGDHTTTRIP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10809574-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2020-10-20 US disclosed
US-20190233731-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2019-08-01 US disclosed