Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341383 | 0.82 | NOS3 (0.45) | NOS3NOS2HMGCR | |
| SCHEMBL13812332 | 0.75 | HMGCR (0.49) | NOS3NOS2HMGCR | |
| SCHEMBL18469231 | 0.75 | NOS3 (0.44) | NOS3NOS2HMGCR | |
| SCHEMBL13184849 | 0.73 | NOS3 (0.38) | NOS3NOS2HMGCR | |
| SCHEMBL24626775 | 0.67 | CTSK (0.44) | — | |
| SCHEMBL22545108 | 0.63 | ADORA2A (0.33) | — | |
| SCHEMBL327924 | 0.63 | CYP1A2 (0.34) | NOS3NOS2 | |
| SCHEMBL10286005 | 0.63 | NOS3 (0.31) | NOS3NOS2 | |
| SCHEMBL24394419 | 0.62 | TLR8 (0.33) | NOS3NOS2 | |
| SCHEMBL3289190 | 0.62 | NOS3 (0.31) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148125-A1 | SREBP INHIBITORS COMPRISING A 6-MEMBERED CENTRAL RING | CAPULUS THERAPEUTICS, LLC (US) | 2019-08-01 | — | — | WO | disclosed |