Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17339103 | 0.75 | BAZ2B (0.49) | BAZ2BBAZ2AFNTAFNTBTP53 | |
| SCHEMBL10362806 | 0.69 | KCNH2 (0.54) | PDE4APDE4BPDE4CPDE4DKCNH2 | |
| SCHEMBL26301363 | 0.69 | FNTA (0.57) | SRD5A2BAZ2BBAZ2AFNTAFNTB | |
| SCHEMBL26301329 | 0.69 | FNTA (0.53) | SRD5A2BAZ2BBAZ2AFNTAFNTB | |
| SCHEMBL4208025 | 0.69 | CCR2 (0.74) | CCR9CCR2PPARG | |
| SCHEMBL26302080 | 0.69 | BAZ2B (0.67) | BAZ2BBAZ2ATP53MAPTBRD4 | |
| SCHEMBL2146030 | 0.68 | KCNH2 (0.50) | PDE4APDE4BPDE4CPDE4DKCNH2 | |
| SCHEMBL26301296 | 0.68 | FNTA (0.51) | SRD5A2BAZ2BBAZ2AFNTAFNTB | |
| SCHEMBL12394721 | 0.68 | KCNH2 (0.49) | PDE4APDE4BPDE4CPDE4DKCNH2 | |
| SCHEMBL28249149 | 0.67 | PTPN1 (0.49) | SRD5A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759114-A1 | HETEROBICYCLIC CARBOXYLIC ACIDS AND SALTS THEREOF | Shenzhen Ionova Life Science Co., Ltd. (CN) | 2021-01-06 | — | — | EP | claimed |
| EP-3749323-A1 | HETEROBICYCLIC CARBOXYLIC ACIDS FOR TREATING CANCER OR INFLAMMATORY DISEASES | Shenzhen Ionova Life Science Co., Ltd. (CN) | 2020-12-16 | — | — | EP | claimed |
| WO-2019149286-A1 | HETEROBICYCLIC CARBOXYLIC ACIDS FOR TREATING CANCER OR INFLAMMATORY DISEASES | SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) | 2019-08-08 | — | — | WO | claimed |