Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14331600 | 0.81 | NPC1 (0.44) | PDE10ARUNX1NPC1RAB9ASCN4A | |
| SCHEMBL29991874 | 0.80 | ALDH1A1 (0.56) | NPC1RAB9ALMNABLMSMN1; SMN2 | |
| SCHEMBL621880 | 0.80 | ALDH1A1 (0.56) | NPC1RAB9ALMNABLMSMN1; SMN2 | |
| SCHEMBL8180035 | 0.78 | CYP1A2 (0.50) | NPC1RAB9ASCN4ASCN9AGMNN | |
| SCHEMBL13586988 | 0.77 | HPGDS (0.47) | PDE10ANPC1RAB9ASCN4ASCN9A | |
| SCHEMBL13356521 | 0.77 | CYP1A2 (0.47) | PDE10ARUNX1NPC1RAB9ASCN4A | |
| SCHEMBL32685110 | 0.77 | CYP1A2 (0.52) | PDE10ANPC1RAB9ASCN4ASCN9A | |
| SCHEMBL6192655 | 0.77 | CYP1A2 (0.52) | PDE10ANPC1RAB9ASCN4ASCN9A | |
| SCHEMBL20033417 | 0.75 | KDM4E (0.50) | PDE10ASCN4AMEN1KMT2APDE2A | |
| SCHEMBL29639042 | 0.75 | KDM4E (0.50) | PDE10ASCN4AMEN1KMT2APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152731-A1 | ANDROGEN RECEPTOR ANTAGONISTS | ALPINE ANDROSCIENCES, INC. (US) | 2019-08-08 | — | — | WO | disclosed |