SCHEMBL212272

SCHEMBL212272

O=C(O)CN(CC(=O)O)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
HDAC3 O15379 2/20 0.49
HDAC1 Q13547 2/20 0.49
HDAC2 Q92769 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
NCOR2 Q9Y618 2/20 0.49
LMNA P02545 1/20 0.48
KEAP1 Q14145 1/20 0.48
MEP1B Q16820 1/20 0.47
ALDH1A1 P00352 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL186172 0.98 MEP1B (0.50) AKR1B1NPC1RAB9ACA12CA9
Ammonia Solution, Strong SCHEMBL27504556 0.96 MEP1B (0.49) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL2799777 0.94 TDP1 (0.52) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL11586184 0.94 MEP1B (0.47) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL2284795 0.92 TDP1 (0.56) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL12243695 0.92 TDP1 (0.56) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL2807141 0.92 TDP1 (0.56) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL7564337 0.90 TDP1 (0.58) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL16520408 0.90 NPC1 (0.47) AKR1B1NPC1RAB9ACA12CA9
SCHEMBL38659632 0.90 AKR1B1 (0.43) AKR1B1NPC1RAB9ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10464958-B2 Method for the synthesis of alpha-aminoalkylenephosphonic acid MONSANTO TECHNOLOGY LLC (US) 2019-11-05 US claimed
US-20180346497-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC (US) 2018-12-06 US claimed
CN-104812765-B Process for the synthesis of alpha-aminoalkylenephosphonic acid 斯特雷特马克控股股份公司 2017-06-06 CN claimed
US-9133377-B2 Adhesive polyurethane powder capable of being activated by heat A. RAYMOND ET CIE (FR) 2015-09-15 US claimed
US-20150232493-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC 2015-08-20 US claimed
CN-104812765-A Process for the synthesis of alpha-aminoalkylenephosphonic acid STRAITMARK HOLDING AG 2015-07-29 CN claimed
EP-2875035-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID Straitmark Holding AG (CH) 2015-05-27 EP claimed
WO-2014012990-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID STRAITMARK HOLDING AG (CH) 2014-01-23 WO claimed
WO-2011085445-A1 FLOTATION REAGENTS TEEBEE HOLDINGS PTY LTD (AU) 2011-07-21 WO claimed
EP-1249343-B1 Thermal initiator system using leuco dyes and polyhalogene compounds KODAK GRAPHIC COMM GMBH (DE) 2008-07-23 EP claimed
US-5821074-A ANALYZING FOR LEAD ABBOTT LABORATORIES (US) 1998-10-13 US claimed
US-5703095-A PREVENTION FERRITIN FROM RELEASING OXYGEN L'OREAL (FR) 1997-12-30 US claimed
US-5602192-A BLEND OF PHENOLIC BINDER AND ADJUVANT KAO CORPORATION (JP) 1997-02-11 US claimed
US-5597702-A ENZYME INHIBITOR ABBOTT LABORATORIES (US) 1997-01-28 US claimed
EP-0434561-B1 1-Naphthyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1995-10-18 EP claimed
EP-0130482-B1 DIAMINOCYCLOHEXANE PLATINUM COMPLEXES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Research Corporation (US) 1988-12-28 EP claimed
US-4758588-A Diaminocyclohexane platinum complexes RESEARCH CORPORATION TECHNOLOGIES (US) 1988-07-19 US claimed
US-4661516-A WATER SOLUBLE, ANTITUMOR AGENTS RESEARCH CORPORATION (US) 1987-04-28 US claimed
US-4285575-A USING AN ELECTROCHROMIC ELECTROLYTE CONTAINING A CARBOXYLIC-CONTAINING COMPLEXING AGENT, A FERROUS SALT, A METAL SALT, AND A CHROMOGEN; DURABILITY CANON KABUSHIKI KAISHA (JP) 1981-08-25 US claimed
US-4212518-A ELECTROCHROMIC CELL CANON KABUSHIKI KAISHA (JP) 1980-07-15 US claimed