Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28715306 | 0.77 | MKNK1 (0.39) | RAB9ANPC1ELANEL3MBTL1DHODH | |
| SCHEMBL16481976 | 0.74 | BTK (0.42) | BTKRAB9ANPC1HRH4GABRA1 | |
| SCHEMBL2121707 | 0.74 | BTK (0.42) | BTKRAB9ANPC1HRH4CA1 | |
| SCHEMBL14877222 | 0.74 | POLB (0.36) | RAB9ANPC1CA1CA2DHODH | |
| SCHEMBL29840676 | 0.74 | METAP2 (0.49) | RAB9ANPC1CA1CA2L3MBTL1 | |
| SCHEMBL2124969 | 0.74 | METAP2 (0.49) | RAB9ANPC1CA1CA2L3MBTL1 | |
| SCHEMBL29335082 | 0.74 | MAPT (0.40) | NPC1DHODHCYP1A2CYP2D6CYP19A1 | |
| SCHEMBL1807936 | 0.74 | TRIM24 (0.36) | RAB9ANPC1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL6206420 | 0.73 | BTK (0.44) | BTKRAB9ANPC1HRH4CA1 | |
| SCHEMBL15344911 | 0.73 | CCR1 (0.52) | BTKRAB9ANPC1HRH4GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095011-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095011-A1 | NOVEL COMPOUNDS | C1R, TBXA2R, F12 | BTK 3365/4885RAB9A 618/4885NPC1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.