Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248337 | 0.81 | TP53 (0.62) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL810345 | 0.81 | KMT2A (0.69) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL440008 | 0.78 | KMT2A (0.42) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL1227312 | 0.78 | KDM4E (0.38) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL31279583 | 0.78 | KMT2A (0.42) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL8397028 | 0.76 | KMT2A (0.42) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL25204937 | 0.75 | KDM4E (0.45) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL2480844 | 0.75 | KDM4E (0.45) | KMT2AKDM4EGAAHSD17B10TSHR | |
| SCHEMBL3970187 | 0.75 | LRRK2 (0.44) | TP53KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL584580 | 0.75 | CSNK1A1 (0.60) | TP53KMT2AKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727435-B1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | UNIV CARNEGIE MELLON (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20250152593-A1 | p38 MAPK INHIBITORS AND USES THEREOF | HOPE CITY (US) | 2025-05-15 | — | — | US | disclosed |
| CN-111757935-B | Bivalent nucleic acid ligands and uses thereof | 卡耐基梅隆大学 | 2025-02-21 | — | — | CN | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-3727435-A1 | BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR | CARNEGIE MELLON UNIVERSITY (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-111757935-A | Bivalent nucleic acid ligand and use thereof | 卡耐基梅隆大学 | 2020-10-09 | — | — | CN | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| US-20200318195-A1 | Bivalent Nucleic Acid Ligands and Uses Therefor | CARNEGIE MELLON UNIVERSITY | 2020-10-08 | — | — | US | disclosed |
| US-10370415-B2 | Divalent nucleobase compounds and uses therefor | CARNEGIE MELLON UNIVERSITY (US) | 2019-08-06 | — | — | US | disclosed |
| EP-2376493-B1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE | MSD KK (JP) | 2016-10-05 | — | — | EP | disclosed |
| EP-1651648-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2006-05-03 | — | — | EP | disclosed |
| US-20050245518-A1 | Antiproliferative agents | METHYLGENE, INC. | 2005-11-03 | — | — | US | disclosed |
| WO-2005092899-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2005-10-06 | — | — | WO | disclosed |
| US-20050222177-A1 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2005-10-06 | — | — | US | disclosed |
| US-20050187230-A1 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2005-08-25 | — | — | US | disclosed |
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |
| WO-2005034869-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2005-04-21 | — | — | WO | disclosed |
| WO-2005011597-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2005-02-10 | — | — | WO | disclosed |
| US-20040044012-A1 | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation | DOBRUSIN ELLEN MYRA (US) | 2004-03-04 | — | — | US | disclosed |
| US-4323681-A | IMMUNOMODULATOR AGENTS HAVING STIMULANT OR SUPPRESSANT EFFECT FOR TREATMENT OF AUTOIMMUNE DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044012-A1 | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation | CCNI, CCNH, CCNA1 | TP53 375/4885KMT2A 2878/4885KDM4E 3108/4885 |
| US-20050187230-A1 | Compounds and compositions as protein kinase inhibitors | FYN, LCK, SRC | TP53 890/4885KMT2A 1842/4885KDM4E 1492/4885 |
| US-20250152593-A1 | p38 MAPK INHIBITORS AND USES THEREOF | MAPK8, MAPK1, MAPK7 | TP53 982/4885KMT2A 2691/4885KDM4E 4299/4885 |
| US-10370415-B2 | Divalent nucleobase compounds and uses therefor | DNTT, POLM, POLL | TP53 553/4885KMT2A 2921/4885KDM4E 4851/4885 |
| US-20050245518-A1 | Antiproliferative agents | HDAC1, HDAC11, HDAC5 | TP53 115/4885KMT2A 123/4885KDM4E 337/4885 |
| US-20050222177-A1 | Compounds and compositions as protein kinase inhibitors | BMX, FES, FRK | TP53 1115/4885KMT2A 2082/4885KDM4E 2488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.