Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212306 | 0.81 | TP53 (0.58) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL810345 | 0.77 | KMT2A (0.69) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL263835 | 0.74 | CSNK1A1 (0.64) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL811481 | 0.72 | ALDH1A1 (0.78) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL584580 | 0.71 | CSNK1A1 (0.60) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL19837459 | 0.71 | CSNK1A1 (0.60) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL28939398 | 0.71 | CSNK1A1 (0.60) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL1143429 | 0.71 | CSNK1A1 (1.00) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL1143690 | 0.71 | CSNK1A1 (0.60) | TP53GAAKMT2AHSD17B10TSHR | |
| SCHEMBL31492947 | 0.71 | CSNK1A1 (0.60) | TP53GAAKMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |