Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 3/20 | 0.58 |
| ▸ | MMP9 | P14780 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22674651 | 0.89 | FOLH1 (0.60) | FOLH1SIRT2MMP2MMP9HTT | |
| SCHEMBL7318212 | 0.87 | FOLH1 (0.58) | FOLH1SIRT2MMP2MMP9HTT | |
| SCHEMBL7311020 | 0.87 | FOLH1 (0.58) | FOLH1SIRT2MMP2MMP9HTT | |
| SCHEMBL23505268 | 0.86 | FOLH1 (0.60) | FOLH1SIRT2MMP2MMP9HTT | |
| SCHEMBL7316398 | 0.85 | SIRT2 (0.56) | FOLH1SIRT2MMP2MMP9HTT | |
| SCHEMBL4177378 | 0.85 | DPP8 (0.68) | FOLH1MMP2MMP9HTTDPP8 | |
| SCHEMBL4177384 | 0.85 | DPP8 (0.68) | FOLH1MMP2MMP9HTTDPP8 | |
| SCHEMBL8120405 | 0.84 | HTT (0.56) | FOLH1SIRT2MMP2MMP9HTT | |
| SCHEMBL9738257 | 0.84 | FOLH1 (0.61) | FOLH1SIRT2MMP2MMP9HTT | |
| SCHEMBL9738268 | 0.84 | FOLH1 (0.61) | FOLH1SIRT2MMP2MMP9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149781-A1 | MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE | SANOFI (FR) | 2019-08-08 | — | — | WO | disclosed |