Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311020 | 0.86 | FOLH1 (0.58) | SIRT2FOLH1MMP2MMP9HTT | |
| SCHEMBL7318212 | 0.86 | FOLH1 (0.58) | SIRT2FOLH1MMP2MMP9HTT | |
| SCHEMBL21231838 | 0.85 | FOLH1 (0.61) | SIRT2FOLH1MMP2MMP9HTT | |
| SCHEMBL8120405 | 0.84 | HTT (0.56) | SIRT2FOLH1MMP2MMP9HTT | |
| SCHEMBL22674651 | 0.84 | FOLH1 (0.60) | SIRT2FOLH1MMP2MMP9HTT | |
| SCHEMBL23505268 | 0.81 | FOLH1 (0.60) | SIRT2FOLH1MMP2MMP9HTT | |
| SCHEMBL7316399 | 0.81 | ANPEP (0.64) | FOLH1HTTDPP8DPP7TGM2 | |
| Hydrochloric Acid SCHEMBL8068240 | 0.81 | HTT (0.53) | SIRT2FOLH1MMP2MMP9HTT | |
| SCHEMBL17073781 | 0.81 | CTSL (0.63) | SIRT2FOLH1MMP2MMP9DPP8 | |
| SCHEMBL8111499 | 0.80 | HTT (0.52) | SIRT2FOLH1MMP2MMP9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |