Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.61 |
| ▸ | MMP2 | P08253 | 3/20 | 0.58 |
| ▸ | MMP9 | P14780 | 3/20 | 0.58 |
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738268 | 1.00 | FOLH1 (0.61) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL9738061 | 0.88 | FOLH1 (0.60) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL9738069 | 0.88 | FOLH1 (0.60) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL7311020 | 0.85 | FOLH1 (0.58) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL7318212 | 0.85 | FOLH1 (0.58) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL21231838 | 0.84 | FOLH1 (0.61) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL15834382 | 0.83 | SIRT2 (0.59) | FOLH1SIRT2HTT | |
| SCHEMBL15804488 | 0.83 | HTT (0.52) | FOLH1MMP2MMP9SIRT2HTT | |
| SCHEMBL22674651 | 0.83 | FOLH1 (0.60) | FOLH1MMP2MMP9CPB1CPB2 | |
| SCHEMBL7377576 | 0.81 | MME (0.47) | FOLH1MMP2MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151432-A | Cognition activators to improve memory, inhibitors of angiotensin converting enzymes, cardiovascular disorders and learning dysfunction | ADIR ET COMPAGNIE (FR) | 1992-09-29 | — | — | US | disclosed |