Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | HINT1 | P49773 | 3/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941721 | 1.00 | ADORA3 (0.48) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL13523344 | 0.88 | ADORA3 (0.48) | ADORA3HINT1STING1PDE3BPDE3A | |
| SCHEMBL465582 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E | |
| SCHEMBL20991026 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E | |
| SCHEMBL19813683 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E | |
| SCHEMBL25380147 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E | |
| SCHEMBL13929032 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E | |
| SCHEMBL471141 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E | |
| SCHEMBL15038040 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E | |
| SCHEMBL15187537 | 0.86 | ADORA2A (0.51) | ADORA3HINT1STING1PNPNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521297-A1 | MODIFIED FLUORINATED NUCLEOSIDE ANALOGUES | Gilead Pharmasset LLC (US) | 2019-08-07 | — | — | EP | disclosed |