Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.48 |
| ▸ | HINT1 | P49773 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12151766 | 0.90 | ADORA3 (0.49) | ADORA3STING1HINT1ADORA2APDE3B | |
| SCHEMBL16330663 | 0.90 | ADORA3 (0.49) | ADORA3STING1HINT1ADORA2APDE3B | |
| SCHEMBL15941721 | 0.88 | ADORA3 (0.48) | ADORA3STING1HINT1PDE3BPDE3A | |
| SCHEMBL21232906 | 0.88 | ADORA3 (0.48) | ADORA3STING1HINT1PDE3BPDE3A | |
| 2'-B-Methyl-Guanosine SCHEMBL14853673 | 0.86 | ADORA2A (0.65) | ADORA3STING1HINT1ADORA2ANT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL21007207 | 0.86 | ADORA2A (0.65) | ADORA3STING1HINT1ADORA2ANT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL18537392 | 0.86 | ADORA2A (0.65) | ADORA3STING1HINT1ADORA2ANT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL14842089 | 0.86 | ADORA2A (0.65) | ADORA3STING1HINT1ADORA2ANT5E | |
| SCHEMBL15019642 | 0.86 | ADORA2A (0.54) | ADORA3STING1HINT1ADORA2APDE3B | |
| 2'-B-Methyl-Guanosine SCHEMBL12758165 | 0.86 | ADORA2A (0.65) | ADORA3STING1HINT1ADORA2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003217-A1 | Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections | CRETTON-SCOTT ERIKA | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003217-A1 | Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections | HAVCR2, PYGL, GOT1 | ADORA3 1277/4885STING1 146/4885HINT1 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.