Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 4/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278130 | 0.92 | HINT1 (0.62) | HINT1STING1PDE3BPDE3ANT5E | |
| SCHEMBL19938159 | 0.92 | HINT1 (0.62) | HINT1STING1PDE3BPDE3ANT5E | |
| SCHEMBL2510562 | 0.92 | HINT1 (0.62) | HINT1STING1PDE3BPDE3ANT5E | |
| SCHEMBL16114092 | 0.92 | HINT1 (0.62) | HINT1STING1PDE3BPDE3ANT5E | |
| SCHEMBL13833323 | 0.92 | HINT1 (0.62) | HINT1STING1PDE3BPDE3ANT5E | |
| SCHEMBL24299397 | 0.92 | HINT1 (0.62) | HINT1STING1PDE3BPDE3ANT5E | |
| SCHEMBL27221934 | 0.91 | HINT1 (0.61) | HINT1STING1PDE3BPDE3ANT5E | |
| Phosphoric Acid SCHEMBL25402859 | 0.88 | NT5E (0.63) | HINT1STING1PDE3BPDE3ANT5E | |
| Phosphoric Acid SCHEMBL1299515 | 0.88 | NT5E (0.63) | HINT1STING1PDE3BPDE3ANT5E | |
| SCHEMBL412371 | 0.87 | HPGD (0.62) | HINT1STING1PDE3BPDE3ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521297-A1 | MODIFIED FLUORINATED NUCLEOSIDE ANALOGUES | Gilead Pharmasset LLC (US) | 2019-08-07 | — | — | EP | disclosed |