SCHEMBL2510562

SCHEMBL2510562

C[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ HINT1 P49773 5/20 0.62
▸ ADORA3 P0DMS8 1/20 0.61
▸ NT5E P21589 1/20 0.59
▸ STING1 Q86WV6 3/20 0.58
▸ PDE3B Q13370 1/20 0.58
▸ PDE3A Q14432 1/20 0.58
▸ TAAR1 Q96RJ0 1/20 0.57
▸ GSK3A P49840 2/20 0.55
▸ RPS6KA3 P51812 2/20 0.55
▸ MAPK14 Q16539 2/20 0.55
▸ TGM2 P21980 1/20 0.55
▸ HPGD P15428 1/20 0.54
▸ PNP P00491 1/20 0.53
▸ FUT5 Q11128 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4278130 1.00 HINT1 (0.62) HINT1ADORA3NT5ESTING1PDE3B
SCHEMBL24299397 1.00 HINT1 (0.62) HINT1ADORA3NT5ESTING1PDE3B
SCHEMBL16114092 1.00 HINT1 (0.62) HINT1ADORA3NT5ESTING1PDE3B
SCHEMBL19938159 1.00 HINT1 (0.62) HINT1ADORA3NT5ESTING1PDE3B
SCHEMBL13833323 1.00 HINT1 (0.62) HINT1ADORA3NT5ESTING1PDE3B
SCHEMBL27221934 0.99 HINT1 (0.61) HINT1ADORA3NT5ESTING1PDE3B
Phosphoric Acid SCHEMBL1299515 0.96 NT5E (0.63) HINT1ADORA3NT5ESTING1PDE3B
Phosphoric Acid SCHEMBL25402859 0.96 NT5E (0.63) HINT1ADORA3NT5ESTING1PDE3B
SCHEMBL21232923 0.92 HINT1 (0.56) HINT1ADORA3NT5ESTING1PDE3B
Phosphoric Acid SCHEMBL17505120 0.92 NT5E (0.61) HINT1ADORA3NT5ESTING1PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118638898-A Method for targeted nucleic acid sequence enrichment and use in error-correcting nucleic acid sequencing 华盛顿大学 2024-09-13 — — CN disclosed
CN-110520542-B Method for targeted nucleic acid sequence enrichment and use in error-correcting nucleic acid sequencing 华盛顿大学 2024-06-14 — — CN disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 — — US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 — — EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 — — WO disclosed
WO-2014160200-A9 RAS INHIBITORS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2014-11-27 — — WO disclosed
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 — — US disclosed
WO-2014160200-A1 RAS INHIBITORS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2014-10-02 — — WO disclosed
US-20130028920-A1 STABILIZED ANTIBODY PREPARATIONS AND USES THEREOF UNIVERSITE DE GENEVE (CH) 2013-01-31 — — US disclosed
US-20130017197-A1 STABILIZED ANTIBODY PREPARATIONS AND USES THEREOF UNIVERSITE DE GENEVE (CH) 2013-01-17 — — US disclosed
US-20110246081-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-06 — — US disclosed
US-20090118140-A1 METHOD AND SYSTEM FOR ASSEMBLY OF MACROMOLECULES AND NANOSTRUCTURES XF TECHNOLOGIES INC. 2009-05-07 — — US disclosed
WO-2009052186-A1 METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS GEORGIA TECH RESEARCH CORPORATION (US) 2009-04-23 — — WO disclosed
WO-2008112980-A2 METHOD AND SYSTEM FOR ASSEMBLY OF MACROMOLECULES AND NANOSTRUCTURES INCITOR, LLC (US) 2008-09-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130017197-A1 STABILIZED ANTIBODY PREPARATIONS AND USES THEREOF FCGRT, IGLV6-57, FCGR3B HINT1 2950/4885ADORA3 2620/4885NT5E 955/4885
US-20130028920-A1 STABILIZED ANTIBODY PREPARATIONS AND USES THEREOF FCGRT, IGLV6-57, FCGR3B HINT1 2950/4885ADORA3 2620/4885NT5E 955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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