Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367048 | 0.83 | ADORA2A (0.36) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL23354111 | 0.81 | ADORA2A (0.35) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL23354108 | 0.80 | ADORA2A (0.35) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL23354371 | 0.79 | L3MBTL1 (0.44) | RAB9ANPC1KDM4ETP53HSD17B10 | |
| SCHEMBL18994374 | 0.78 | GAA (0.49) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL2516609 | 0.78 | ADORA2A (0.55) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL18723264 | 0.78 | LMNA (0.36) | ADORA2AADORA1RAB9ANPC1KDM4E | |
| SCHEMBL631704 | 0.78 | KDM4E (0.39) | ADORA2AADORA1RAB9ANPC1KDM4E | |
| SCHEMBL22952818 | 0.77 | HTR2A (0.36) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL18723265 | 0.77 | L3MBTL1 (0.46) | RAB9ANPC1KDM4ETP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |