Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952685 | 0.77 | CNR1 (0.31) | KDM4E | |
| SCHEMBL12050005 | 0.72 | ALDH1A1 (0.65) | ALDH1A1LMNABAZ2BMAP3K5MAPT | |
| SCHEMBL17811622 | 0.69 | ALDH1A1 (0.67) | ALDH1A1LMNABAZ2BMAP3K5KMT2A | |
| SCHEMBL12614629 | 0.69 | ALDH1A1 (0.45) | ALDH1A1LMNABAZ2BBCHEMAP3K5 | |
| SCHEMBL22952684 | 0.69 | — | — | |
| SCHEMBL21233059 | 0.67 | BAZ2B (0.39) | ALDH1A1LMNABAZ2BBCHEKDM4E | |
| SCHEMBL17115786 | 0.67 | LMNA (0.50) | ALDH1A1LMNABAZ2BBCHEMAP3K5 | |
| SCHEMBL10274568 | 0.67 | ALDH1A1 (0.63) | ALDH1A1LMNABAZ2BMAP3K5KMT2A | |
| SCHEMBL21780784 | 0.67 | ALDH1A1 (0.54) | ALDH1A1LMNABAZ2BBCHEKMT2A | |
| SCHEMBL12050008 | 0.66 | ALDH1A1 (0.61) | ALDH1A1LMNABAZ2BMAP3K5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |