Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31597293 | 0.83 | HDAC6 (0.32) | TSHRRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL15813458 | 0.82 | TSHR (0.39) | TSHRRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL22951298 | 0.78 | TSHR (0.36) | TSHRRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL15813726 | 0.74 | MAPT (0.35) | TSHRRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL26051626 | 0.73 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1NOTUM | |
| SCHEMBL21241221 | 0.71 | BRD4 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL14401143 | 0.70 | NOTUM (0.44) | TSHRRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL26206453 | 0.68 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL21233330 | 0.68 | LMNA (0.42) | SMN1; SMN2ALDH1A1LMNANOTUMMEN1 | |
| SCHEMBL21233180 | 0.68 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |