Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 3/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952419 | 0.78 | BRD4 (0.39) | CYP11B2BRD4CCNCCDK8HPGDS | |
| SCHEMBL26765907 | 0.73 | CYP11B2 (0.40) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL21233161 | 0.71 | CYP11B2 (0.39) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL21233163 | 0.71 | TSHR (0.44) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL26776554 | 0.70 | CYP11B2 (0.38) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL21233352 | 0.69 | CYP11B2 (0.43) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL26195686 | 0.69 | CYP11B2 (0.44) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL21241221 | 0.68 | BRD4 (0.36) | ALDH1A1BRD4CCNCCDK8HPGDS | |
| SCHEMBL21233345 | 0.68 | KDM4E (0.44) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL15345069 | 0.68 | CCR1 (0.55) | KDM4EALDH1A1POLBGAAAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |