Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952430 | 0.78 | CYP11B2 (0.31) | CYP11B2 | |
| SCHEMBL26765907 | 0.73 | CYP11B2 (0.40) | CYP11B2MAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL21233282 | 0.71 | KDM4E (0.43) | CYP11B2MAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL26776554 | 0.70 | CYP11B2 (0.38) | CYP11B2MAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL21233156 | 0.69 | CYP11B2 (0.43) | CYP11B2MAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL26195686 | 0.69 | CYP11B2 (0.44) | CYP11B2MAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL21233354 | 0.68 | CYP11B2 (0.42) | CYP11B2MAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL20507210 | 0.68 | KDM4E (0.42) | CYP11B2ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL21233163 | 0.68 | TSHR (0.44) | CYP11B2MAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL21233180 | 0.68 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |