SCHEMBL2123433

SCHEMBL2123433

CCOCCSSCCOCC

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11206336 0.89 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL12765924 0.87 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL12337808 0.85
SCHEMBL12456984 0.81 HTT (0.48) ALDH1A1TSHRTHRB
SCHEMBL12456981 0.81 HTT (0.48) ALDH1A1TSHRTHRB
SCHEMBL7546724 0.80 ALDH1A1 (0.45) ALDH1A1TSHRTHRB
SCHEMBL10712846 0.79 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL7101023 0.78 ALDH1A1 (0.43) ALDH1A1TSHRTHRB
SCHEMBL12852155 0.78 ALDH1A1 (0.43) ALDH1A1TSHRTHRB
SCHEMBL3390773 0.78 HSD17B10 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801508-B2 Covalently modified surfaces, kits, and methods of preparation and use Berkeley Lights, Inc. (US) 2023-10-31 US disclosed
WO-2017205830-A1 COVALENTLY MODIFIED SURFACES, KITS, AND METHODS OF PREPARATION AND USE Berkeley Lights, Inc. (US) 2017-11-30 WO disclosed
EP-2145765-B1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving. relief printing plate, and method of producing relief printing plate FUJIFILM CORP (JP) 2016-12-07 EP disclosed
US-8735388-B2 Heterocyclic compounds with affinity to muscarinic receptors ABBVIE B.V. (NL) 2014-05-27 US disclosed
US-20140080861-A1 HETEROCYCLIC COMPOUNDS IWTH AFFINITY TO MUSCARINIC RECEPTORS ABBVIE B.V.A (NL) 2014-03-20 US disclosed
US-8586606-B2 Heterocyclic compounds with affinity to muscarinic receptors ABBVIE B.V. (NL) 2013-11-19 US disclosed
US-8367300-B2 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of producing relief printing plate FUJIFILM CORPORATION (JP) 2013-02-05 US disclosed
US-8367300-B2 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of producing relief printing plate FUJIFILM CORPORATION (JP) 2013-02-05 US disclosed
EP-2168764-B1 Relief printing plate precursor for laser engraving, method of producing the same and method of producing relief printing plate FUJIFILM CORP (JP) 2012-10-31 EP disclosed
US-8278387-B2 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2012-10-02 US disclosed
US-20100015416-A1 RESIN COMPOSITION FOR LASER ENGRAVING, IMAGE FORMING MATERIAL, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE, AND METHOD OF PRODUCING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
EP-2145765-A1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving. relief printing plate, and method of producing relief printing plate FUJIFILM Corporation (JP) 2010-01-20 EP disclosed
US-20090246469-A1 RESIN COMPOSITION FOR LASER ENGRAVING, IMAGE FORMING MATERIAL, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE, AND METHOD OF MANUFACTURING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246469-A1 RESIN COMPOSITION FOR LASER ENGRAVING, IMAGE FORMING MATERIAL, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE, AND METHOD OF MANUFACTURING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105795-A1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM Corporation (JP) 2009-09-30 EP disclosed
US-20090018160-A1 Heterocyclic Compounds with Affinity to Muscarinic Receptors ABBVIE B.V. (NL) 2009-01-15 US disclosed
WO-2008129054-A2 HETEROCYCLIC COMPOUNDS WITH AFFINITY TO MUSCARINIC RECEPTORS SOLVAY PHARMACEUTICALS B.V. (NL) 2008-10-30 WO disclosed
EP-0592933-B1 Method for the preparation of thiol(meth)acrylates ROEHM GMBH (DE) 1996-09-04 EP disclosed
EP-0592933-A1 Method for the preparation of thiol(meth)acrylates RÖHM GMBH (DE) 1994-04-20 EP disclosed
US-4399075-A Process for producing chlorinated phenoxytoluene derivatives ASAHI CHEMICAL COMPANY, LIMITED (JP) 1983-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140080861-A1 HETEROCYCLIC COMPOUNDS IWTH AFFINITY TO MUSCARINIC RECEPTORS CHRM3, CHRM4, CHRM5 ALDH1A1 1428/4885TSHR 199/4885THRB 438/4885
US-20090018160-A1 Heterocyclic Compounds with Affinity to Muscarinic Receptors CHRM3, CHRM2, CHRM1 ALDH1A1 3609/4885TSHR 41/4885THRB 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.