Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563498 | 1.00 | ENPP2 (0.59) | ENPP2CA2CA1HTTTDP1 | |
| SCHEMBL31563612 | 0.85 | CA1 (0.67) | ENPP2CA2CA1ALDH1A1KDM4E | |
| SCHEMBL257834 | 0.85 | CA1 (0.67) | ENPP2CA2CA1ALDH1A1KDM4E | |
| SCHEMBL257603 | 0.82 | CA2 (0.63) | ENPP2CA2CA1HTTTDP1 | |
| SCHEMBL5002492 | 0.82 | ENPP2 (0.55) | ENPP2CA2CA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8388427 | 0.82 | ENPP2 (0.55) | ENPP2CA2CA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21234447 | 0.81 | ENPP2 (0.54) | ENPP2CA2CA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21234446 | 0.81 | ENPP2 (0.54) | ENPP2CA2CA1HTTALDH1A1 | |
| SCHEMBL257916 | 0.81 | CA2 (0.73) | ENPP2CA2CA1HTTTDP1 | |
| SCHEMBL83816 | 0.80 | TDP1 (0.61) | HTTTDP1L3MBTL1ALDH1A1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472266-A | Compounds as prolyl hydroxylase inhibitors and methods of making the same | 苏中药业集团股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-10617706-B2 | Compounds for cancer chemotherapeutic sensitization | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190240244-A1 | COMPOUNDS FOR CANCER CHEMOTHERAPEUTIC SENSITIZATION | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617706-B2 | Compounds for cancer chemotherapeutic sensitization | ABCC1, MCL1, ABCC3 | ENPP2 2791/4885CA2 3984/4885CA1 3508/4885 |
| US-20190240244-A1 | COMPOUNDS FOR CANCER CHEMOTHERAPEUTIC SENSITIZATION | ABCC1, MCL1, ABCC3 | ENPP2 2791/4885CA2 3984/4885CA1 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.