Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965725 | 0.83 | XDH (0.55) | XDHCYP1A2ALPLGAAGLA | |
| SCHEMBL21225422 | 0.81 | EIF4A3 (0.54) | EIF4A3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL16235908 | 0.80 | HRH4 (0.56) | XDHCYP1A2ALPLHRH4 | |
| SCHEMBL25427384 | 0.79 | CYP1A2 (0.44) | XDHCYP1A2ALPLGAAGLA | |
| SCHEMBL30310723 | 0.78 | XDH (0.47) | XDHCYP1A2ALPLGAAGLA | |
| SCHEMBL7673791 | 0.78 | XDH (0.47) | XDHCYP1A2ALPLGAAGLA | |
| SCHEMBL16235851 | 0.78 | XDH (0.51) | XDHCYP1A2ALPLGAAGLA | |
| SCHEMBL31219118 | 0.78 | XDH (0.51) | XDHCYP1A2ALPLGAAGLA | |
| SCHEMBL24843559 | 0.78 | XDH (0.56) | XDHCYP1A2ALPLGAAGLA | |
| SCHEMBL20505622 | 0.76 | XDH (0.44) | XDHCYP1A2ALPLGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152883-A1 | INHIBITORS OF PROTEIN ARGININE DEIMINASES | PADFORWARD LLC (US) | 2019-08-08 | — | — | WO | disclosed |