Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.47 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673791 | 1.00 | XDH (0.47) | XDHEIF4A3CDK1CCNB1ALPL | |
| SCHEMBL4041607 | 0.85 | CDK1 (0.61) | EIF4A3CDK1CCNB1ALPLGLA | |
| SCHEMBL8959558 | 0.82 | XDH (0.47) | XDHEIF4A3CDK1CCNB1ALPL | |
| SCHEMBL24019964 | 0.82 | ALOX15 (0.58) | EIF4A3CDK1CCNB1ALPLMAPT | |
| SCHEMBL30310477 | 0.81 | EIF4A3 (0.61) | EIF4A3MAPT | |
| SCHEMBL7677228 | 0.81 | EIF4A3 (0.61) | EIF4A3MAPT | |
| SCHEMBL24740100 | 0.79 | ALOX15 (0.58) | EIF4A3CDK1CCNB1MAPTALOX15 | |
| SCHEMBL16236158 | 0.79 | HRH4 (0.56) | XDHCDK1CCNB1ABL1SRC | |
| SCHEMBL3544290 | 0.79 | RHEB (0.47) | CYP1A2MAPT | |
| SCHEMBL21235447 | 0.78 | XDH (0.55) | XDHEIF4A3ALPLABL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |